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Parenterally Administered P24-VP8* Nanoparticle Vaccine Conferred Strong Protection against Rotavirus Diarrhea and Virus Shedding in Gnotobiotic Pigs

Current live rotavirus vaccines are costly with increased risk of intussusception due to vaccine replication in the gut of vaccinated children. New vaccines with improved safety and cost-effectiveness are needed. In this study, we assessed the immunogenicity and protective efficacy of a novel P24-VP...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Ramesh, Ashwin, Mao, Jiangdi, Lei, Shaohua, Twitchell, Erica, Shiraz, Ashton, Jiang, Xi, Tan, Ming, Yuan, Lijuan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963946/
https://ncbi.nlm.nih.gov/pubmed/31698824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7040177
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