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Development of new in vitro models of lung protease activity for investigating stability of inhaled biological therapies and drug delivery systems
Proteases play a vital role in lung health and are critically important to the metabolic clearance of inhaled protein-based therapeutics after inhalation. Surprisingly little is known about lung fluid protease composition and there is a consequent lack of biorelevant experimental models, which limit...
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| Publicado no: | Eur J Pharm Biopharm |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6963770/ https://ncbi.nlm.nih.gov/pubmed/31756380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2019.11.005 |
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