Strain-Dependent Impact of G and SH Deletions Provide New Insights for Live-Attenuated HMPV Vaccine Development

Human metapneumovirus (HMPV) is a major pediatric respiratory pathogen with currently no specific treatment or licensed vaccine. Different strategies to prevent this infection have been evaluated, including live-attenuated vaccines (LAV) based on SH and/or G protein deletions. This approach showed p...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Dubois, Julia, Pizzorno, Andrés, Cavanagh, Marie-Hélène, Padey, Blandine, Nicolas de Lamballerie, Claire, Uyar, Olus, Venable, Marie-Christine, Carbonneau, Julie, Traversier, Aurélien, Julien, Thomas, Lavigne, Sophie, Couture, Christian, Lina, Bruno, Hamelin, Marie-Ève, Terrier, Olivier, Rosa-Calatrava, Manuel, Boivin, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963613/
https://ncbi.nlm.nih.gov/pubmed/31671656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7040164
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