Protective Immunity against Canine Distemper Virus in Dogs Induced by Intranasal Immunization with a Recombinant Probiotic Expressing the Viral H Protein

Canine distemper virus (CDV) elicits a severe contagious disease in a broad range of hosts. CDV mortality rates are 50% in domestic dogs and 100% in ferrets. Its primary infection sites are respiratory and intestinal mucosa. This study aimed to develop an effective mucosal CDV vaccine using a non-an...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Jiang, Yanping, Jia, Shuo, Zheng, Dianzhong, Li, Fengsai, Wang, Shengwen, Wang, Li, Qiao, Xinyuan, Cui, Wen, Tang, Lijie, Xu, Yigang, Xia, Xianzhu, Li, Yijing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963260/
https://ncbi.nlm.nih.gov/pubmed/31835572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7040213
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