iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

The ex vivo production of platelets depleted of human leukocyte antigen class I (HLA-I) could serve as a universal measure to overcome platelet transfusion refractoriness caused by HLA-I incompatibility. Here, we developed human induced pluripotent cell-derived HLA-I-deficient platelets (HLA-KO iPLA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Suzuki, Daisuke, Flahou, Charlotte, Yoshikawa, Norihide, Stirblyte, Ieva, Hayashi, Yoshikazu, Sawaguchi, Akira, Akasaka, Marina, Nakamura, Sou, Higashi, Natsumi, Xu, Huaigeng, Matsumoto, Takuya, Fujio, Kosuke, Manz, Markus G., Hotta, Akitsu, Takizawa, Hitoshi, Eto, Koji, Sugimoto, Naoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962657/
https://ncbi.nlm.nih.gov/pubmed/31883921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.11.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados