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BDNF downregulates β-adrenergic receptor-mediated hypotensive mechanisms in the paraventricular nucleus of the hypothalamus

Brain-derived neurotrophic factor (BDNF) is upregulated in the paraventricular nucleus of the hypothalamus (PVN) in response to hypertensive stimuli such as stress and hyperosmolality, and BDNF acting in the PVN plays a key role in elevating sympathetic activity and blood pressure. However, downstre...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Thorsdottir, Daniella, Cruickshank, Nicholas C., Einwag, Zachary, Hennig, Grant W., Erdos, Benedek
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962618/
https://ncbi.nlm.nih.gov/pubmed/31603352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00478.2019
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