NSAID-induced injury of gastric epithelial cells is reversible: roles of mitochondria, AMP kinase, NGF, and PGE(2)

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (DFN) and indomethacin (INDO) are extensively used worldwide. Their main side effects are injury of the gastrointestinal tract, including erosions, ulcers, and bleeding. Since gastric epithelial cells (GEPCs) are crucial for mucosal de...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Ahluwalia, Amrita, Hoa, Neil, Jones, Michael K., Tarnawski, Andrzej S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962499/
https://ncbi.nlm.nih.gov/pubmed/31545918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00192.2019
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