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Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity
Pancreatic ductal adenocarcinoma (PDAC)’s growing incidence has been linked to the rise in obesity and type 2 diabetes mellitus. In previous work, we have shown that metformin can prevent the increased incidence of PDAC in a Kras(G12D) mouse model subjected to a diet high in fat and calories (HFCD)....
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| 發表在: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6962494/ https://ncbi.nlm.nih.gov/pubmed/31545922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00170.2019 |
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