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Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer

PURPOSE: Pancreatic cancer (PC) is one of the most lethal cancers worldwide, but there are currently no effective treatments. The DNA damage response (DDR) is under investigation for the development of novel anti-cancer drugs. Since DNA repair pathway alterations have been found frequently in PC, th...

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Publicado en:Cancer Res Treat
Autores principales: Jin, Mei Hua, Nam, Ah-Rong, Park, Ji Eun, Bang, Ju-Hee, Bang, Yung-Jue, Oh, Do-Youn
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Cancer Association 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962488/
https://ncbi.nlm.nih.gov/pubmed/31291716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2019.183
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