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Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer

PURPOSE: Pancreatic cancer (PC) is one of the most lethal cancers worldwide, but there are currently no effective treatments. The DNA damage response (DDR) is under investigation for the development of novel anti-cancer drugs. Since DNA repair pathway alterations have been found frequently in PC, th...

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Detalhes bibliográficos
Publicado no:Cancer Res Treat
Main Authors: Jin, Mei Hua, Nam, Ah-Rong, Park, Ji Eun, Bang, Ju-Hee, Bang, Yung-Jue, Oh, Do-Youn
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962488/
https://ncbi.nlm.nih.gov/pubmed/31291716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2019.183
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