Recombinant Alkaline Phosphatase Prevents Acute on Chronic Liver Failure

The lipopolysaccharide (LPS)– toll-like receptor-4 (TLR4) pathway plays an important role in liver failure. Recombinant alkaline phosphatase (recAP) deactivates LPS. The aim of this study was to determine whether recAP prevents the progression of acute and acute-on-chronic liver failure (ACLF). Eigh...

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Publicado en:Sci Rep
Autores principales: Engelmann, Cornelius, Adebayo, Danielle, Oria, Marc, De Chiara, Francesco, Novelli, Simone, Habtesion, Abeba, Davies, Nathan, Andreola, Fausto, Jalan, Rajiv
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962206/
https://ncbi.nlm.nih.gov/pubmed/31942020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57284-z
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