Hemagglutinin-Specific Non-neutralizing Antibody Is Essential for Protection Provided by Inactivated and Viral-Vectored H7N9 Avian Influenza Vaccines in Chickens

Hemagglutination inhibition (HI) and virus neutralization antibody (nAb) do not always correlate with the protection of H7 avian influenza vaccines in mammals and humans. The contribution of different classes of antibodies induced by H7N9 vaccines to protection is poorly characterized in chickens. I...

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Bibliographische Detailangaben
Veröffentlicht in:Front Vet Sci
Hauptverfasser: Hu, Zenglei, Zhao, Jiangyan, Zhao, Yiheng, Fan, Xuelian, Hu, Jiao, Shi, Lei, Wang, Xiaoquan, Liu, Xiaowen, Hu, Shunlin, Gu, Min, Cao, Yongzhong, Liu, Xiufan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Veterinary Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962174/
https://ncbi.nlm.nih.gov/pubmed/31998763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2019.00482
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