Intranasal vaccination with Listeria ivanovii as vector of Mycobacterium tuberculosis antigens promotes specific lung-localized cellular and humoral immune responses

We have previously demonstrated that a recombinant Listeria ivanovii (LI) strain expressing the ESAT-6 or Ag85C protein of Mycobacterium tuberculosis (Mtb) as a tuberculosis (TB) vaccine candidates induced antigen-specific cellular immune responses after intravenous immunization of mice. However, wh...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jiang, Ming-juan, Liu, Si-jing, Su, Lin, Zhang, Xiang, Li, Yong-yu, Tang, Tian, Wang, Chuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962167/
https://ncbi.nlm.nih.gov/pubmed/31942003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57245-6
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