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SOX9 promotes tumor progression through the axis BMI1-p21(CIP)

The developmental regulator SOX9 is linked to cancer progression mainly as a result of its role in the regulation of cancer stem cells (CSCs). However, its activity in the differentiated cells that constitute the heterogeneous tumor bulk has not been extensively studied. In this work, we addressed t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aldaz, Paula, Otaegi-Ugartemendia, Maddalen, Saenz-Antoñanzas, Ander, Garcia-Puga, Mikel, Moreno-Valladares, Manuel, Flores, Juana M., Gerovska, Daniela, Arauzo-Bravo, Marcos J., Samprón, Nicolas, Matheu, Ander, Carrasco-Garcia, Estefania
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962164/
https://ncbi.nlm.nih.gov/pubmed/31941916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57047-w
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