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Functional validity, role, and implications of heavy alcohol consumption genetic loci

High alcohol consumption is a risk factor for morbidity and mortality, yet few genetic loci have been robustly associated with alcohol intake. Here, we use U.K. Biobank (n = 125,249) and GERA (n = 47,967) datasets to determine genetic factors associated with extreme population-level alcohol consumpt...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Thompson, Andrew, Cook, James, Choquet, Hélène, Jorgenson, Eric, Yin, Jie, Kinnunen, Tarja, Barclay, Jeff, Morris, Andrew P., Pirmohamed, Munir
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962045/
https://ncbi.nlm.nih.gov/pubmed/31998841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay5034
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