Ultrastructure of light-activated axons following optogenetic stimulation to produce late-phase long-term potentiation

Analysis of neuronal compartments has revealed many state-dependent changes in geometry but establishing synapse-specific mechanisms at the nanoscale has proven elusive. We co-expressed channelrhodopsin2-GFP and mAPEX2 in a subset of hippocampal CA3 neurons and used trains of light to induce late-ph...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kuwajima, Masaaki, Ostrovskaya, Olga I., Cao, Guan, Weisberg, Seth A., Harris, Kristen M., Zemelman, Boris V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961864/
https://ncbi.nlm.nih.gov/pubmed/31940316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226797
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