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Potentiation of curing by a broad-host-range self-transmissible vector for displacing resistance plasmids to tackle AMR

Plasmids are potent vehicles for spread of antibiotic resistance genes in bacterial populations and often persist in the absence of selection due to efficient maintenance mechanisms. We previously constructed non-conjugative high copy number plasmid vectors that efficiently displace stable plasmids...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lazdins, Alessandro, Maurya, Anand Prakash, Miller, Claire E., Kamruzzaman, Muhammad, Liu, Shuting, Stephens, Elton R., Lloyd, Georgina S., Haratianfar, Mona, Chamberlain, Melissa, Haines, Anthony S., Kreft, Jan-Ulrich, Webber, Mark. A., Iredell, Jonathan, Thomas, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961859/
https://ncbi.nlm.nih.gov/pubmed/31940351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225202
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