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Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome

The protein-level translational status and function of many alternative splicing events remain poorly understood. We use an RNA sequencing (RNA-seq)-guided proteomics method to identify protein alternative splicing isoforms in the human proteome by constructing tissue-specific protein databases that...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lau, Edward, Han, Yu, Williams, Damon R., Thomas, Cody T., Shrestha, Rajani, Wu, Joseph C., Lam, Maggie P.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961840/
https://ncbi.nlm.nih.gov/pubmed/31825849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.026
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