Tumor-Derived Soluble MICA Obstructs the NKG2D Pathway to Restrain NK Cytotoxicity

The natural killer group 2D (NKG2D) receptor and its ligands play important roles in immune surveillance. In this study, we observed that the average serum soluble MICA (sMICA) concentration of 174 hepatocellular carcinoma (HCC) patients was significantly higher than that in 80 healthy subjects (602...

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Detalhes bibliográficos
Publicado no:Aging Dis
Main Authors: Luo, Qizhi, Luo, Weiguang, Zhu, Quan, Huang, Hongjun, Peng, Huiyun, Liu, Rongjiao, Xie, Min, Li, Shili, Li, Ming, Hu, Xiaocui, Zou, Yizhou
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2020
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Orginal Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961768/
https://ncbi.nlm.nih.gov/pubmed/32010486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2019.1017
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