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Author's View: a nuclear transcription factor relocalizing to mitochondria rescues cells from proteotoxic aggregates

Mitochondrial proteostasis is essential for survival, and imbalances can result in severe human diseases. We identified a novel stress response triggered upon accumulation of proteotoxic aggregates in the mitochondrial matrix. Mitochondria-to-nucleus signaling results in a transcriptional response a...

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Bibliografiska uppgifter
I publikationen:Mol Cell Oncol
Huvudupphovsmän: Taskin, Asli Aras, Poveda-Huertes, Daniel, Vögtle, F.-Nora
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961659/
https://ncbi.nlm.nih.gov/pubmed/31993502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1698256
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