Multiple Environmental Signaling Pathways Control the Differentiation of RORγt-Expressing Regulatory T Cells

RORγt-expressing Tregs form a specialized subset of intestinal CD4(+) Foxp3(+) cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota. Recently, c-Maf emerged as a critical factor in the regulation of RORγt expression in Tregs. However, aside from c-Maf signaling,...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Hussein, Hind, Denanglaire, Sébastien, Van Gool, Frédéric, Azouz, Abdulkader, Ajouaou, Yousra, El-Khatib, Hana, Oldenhove, Guillaume, Leo, Oberdan, Andris, Fabienne
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961548/
https://ncbi.nlm.nih.gov/pubmed/31998303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03007
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