Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis

Background: Liposomal amphotericin B (AmBisome®) as a treatment modality for visceral leishmaniasis (VL) has had significant impact on patient care in some but not all regions where VL is endemic.  As the mode of action of AmBisome® in vivo is poorly understood, we compared the tissue-specific trans...

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Vydáno v:Wellcome Open Res
Hlavní autoři: Forrester, Sarah, Siefert, Karin, Ashwin, Helen, Brown, Najmeeyah, Zelmar, Andrea, James, Sally, Lagos, Dimitris, Timmis, Jon, Chatterjee, Mitali, Mottram, Jeremy C., Croft, Simon L., Kaye, Paul M.
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000 Research Limited 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961418/
https://ncbi.nlm.nih.gov/pubmed/31976381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15606.1
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