Identification of a small mutation panel of coding sequences to predict the efficacy of immunotherapy for lung adenocarcinoma

BACKGROUND: Immune checkpoint inhibitors are effective in some cases of lung adenocarcinoma (LUAD). Whole-exome sequencing has revealed that the tumour mutation burden (TMB) is associated with clinical benefits among patients from immune checkpoint inhibitors. Several commercial mutation panels have...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Li, Ying, Jiang, Wenbin, Li, Tianhao, Li, Mengyue, Li, Xin, Zhang, Zheyang, Zhang, Sainan, Liu, Yixin, Zhao, Wenyuan, Gu, Yunyan, Qi, Lishuang, Ao, Lu, Guo, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961230/
https://ncbi.nlm.nih.gov/pubmed/31937321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02199-6
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