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Ongoing inflammation enhances the toxicity of engineered nanomaterials: Application of an in vitro co-culture model of the healthy and inflamed intestine

Chronic inflammatory conditions can negatively impact intestinal barrier function and affect the epithelium's interaction with nano-sized materials. We demonstrate the application of a Caco-2/THP-1 co-culture mimicking the intestine in healthy (i.e. stable) or inflamed state in nanotoxicologica...

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Detalhes bibliográficos
Publicado no:Toxicol In Vitro
Main Authors: Kämpfer, Angela A.M., Urbán, Patricia, La Spina, Rita, Jiménez, Isaac Ojea, Kanase, Nilesh, Stone, Vicki, Kinsner-Ovaskainen, Agnieszka
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961208/
https://ncbi.nlm.nih.gov/pubmed/31760064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2019.104738
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