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Knockout of P2rx7 purinergic receptor attenuates cyst growth in a rat model of ARPKD

The severity of polycystic kidney diseases (PKD) depends on the counterbalancing of genetic predisposition and environmental factors exerting permissive or protective influence on cyst development. One poorly characterized phenomenon in the cystic epithelium is abnormal purinergic signaling. Earlier...

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Détails bibliographiques
Publié dans:Am J Physiol Renal Physiol
Auteurs principaux: Arkhipov, Sergey N., Potter, D’Anna L., Geurts, Aron M., Pavlov, Tengis S.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960783/
https://ncbi.nlm.nih.gov/pubmed/31630543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00395.2019
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