B lymphocytes directly contribute to tissue fibrosis in IgG4-Related Disease

BACKGROUND: IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition marked by rapid clinical improvement after selective depletion of B lymphocytes with rituximab. This feature suggests that B cells might participate in fibrogenesis and wound healing. OBJECTIVE: In the present work we aimed...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Della-Torre, Emanuel, Rigamonti, Elena, Perugino, Cory, Sain, Simona Baghai, Sun, Na, Kaneko, Naoki, Maehara, Takashi, Rovati, Lucrezia, Ponzoni, Maurilio, Milani, Raffaella, Lanzillotta, Marco, Mahajan, Vinay, Mattoo, Hamid, Molineris, Ivan, Deshpande, Vikram, Stone, John H, Falconi, Massimo, Manfredi, Angelo A., Pillai, Shiv
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960365/
https://ncbi.nlm.nih.gov/pubmed/31319101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.07.004
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