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A Novel Hybrid CNN-SVR for CRISPR/Cas9 Guide RNA Activity Prediction
Accurate prediction of guide RNA (gRNA) on-target efficacy is critical for effective application of CRISPR/Cas9 system. Although some machine learning-based and convolutional neural network (CNN)-based methods have been proposed, prediction accuracy remains to be improved. Here, firstly we improved...
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Foilsithe in: | Front Genet |
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Main Authors: | , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Frontiers Media S.A.
2020
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6960259/ https://ncbi.nlm.nih.gov/pubmed/31969902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01303 |
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