RBP2 stabilizes slow Cav1.3 Ca(2+) channel inactivation properties of cochlear inner hair cells

Cav1.3 L-type Ca(2+) channels (LTCCs) in cochlear inner hair cells (IHCs) are essential for hearing as they convert sound-induced graded receptor potentials into tonic postsynaptic glutamate release. To enable fast and indefatigable presynaptic Ca(2+) signaling, IHC Cav1.3 channels exhibit a negativ...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Ortner, Nadine J., Pinggera, Alexandra, Hofer, Nadja T., Siller, Anita, Brandt, Niels, Raffeiner, Andrea, Vilusic, Kristina, Lang, Isabelle, Blum, Kerstin, Obermair, Gerald J., Stefan, Eduard, Engel, Jutta, Striessnig, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Ion Channels, Receptors and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960213/
https://ncbi.nlm.nih.gov/pubmed/31848688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-019-02338-4
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