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3,5-T2—A Janus-Faced Thyroid Hormone Metabolite Exerts Both Canonical T3-Mimetic Endocrine and Intracrine Hepatic Action

Over the last decades, thyroid hormone metabolites (THMs) received marked attention as it has been demonstrated that they are bioactive compounds. Their concentrations were determined by immunoassay or mass-spectrometry methods. Among those metabolites, 3,5-diiodothyronine (3,5-T2), occurs at low na...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Endocrinol (Lausanne)
Hauptverfasser: Köhrle, Josef, Lehmphul, Ina, Pietzner, Maik, Renko, Kostja, Rijntjes, Eddy, Richards, Keith, Anselmo, João, Danielsen, Mark, Jonklaas, Jacqueline
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960127/
https://ncbi.nlm.nih.gov/pubmed/31969860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00787
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