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Secreted calreticulin mutants subvert anticancer immunosurveillance
Mutations of the gene coding for calreticulin (CALR) that cause the loss of the C-terminal KDEL motif abolish its retention in the endoplasmic reticulum and cause CALR to be secreted from cells. Specific CALR mutants bearing a novel C-terminus can precipitate the manifestation of myeloproliferative...
Shranjeno v:
| izdano v: | Oncoimmunology |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959454/ https://ncbi.nlm.nih.gov/pubmed/32002304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1708126 |
| Oznake: |
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