Isolated limb perfusion with melphalan activates interferon-stimulated genes to induce tumor regression in patients with melanoma in-transit metastasis

Hyperthermic isolated limb perfusion (ILP) with high-dose melphalan is a treatment option for melanoma patients with metastasis confined to limbs (in-transit metastasis). The therapy entails a complete response (CR) rate of 50–70%. Cellular immunity is proposed to impact on the clinical efficacy of...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Johansson, Junko, Kiffin, Roberta, Aydin, Ebru, Nilsson, Malin S., Hellstrand, Kristoffer, Lindnér, Per, Naredi, Peter, Olofsson Bagge, Roger, Martner, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959433/
https://ncbi.nlm.nih.gov/pubmed/32002296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1684126
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