Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy

We introduce UnaG as a green-to-dark photoswitching fluorescent protein capable of high-quality super-resolution imaging with photon numbers equivalent to the brightest photoswitchable red protein. UnaG only fluoresces upon binding of a fluorogenic metabolite, bilirubin, enabling UV-free reversible...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Kwon, Jiwoong, Park, Jong-Seok, Kang, Minsu, Choi, Soobin, Park, Jumi, Kim, Gyeong Tae, Lee, Changwook, Cha, Sangwon, Rhee, Hyun-Woo, Shim, Sang-Hee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959352/
https://ncbi.nlm.nih.gov/pubmed/31937765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14067-4
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