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Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

Mucosa-associated invariant T (MAIT) cell loss in chronic HIV-1 infection is a significant insult to antimicrobial immune defenses. Here we investigate the response of MAIT cells during acute HIV-1 infection utilizing the RV217 cohort with paired longitudinal pre- and post-infection samples. MAIT ce...

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發表在:Nat Commun
Main Authors: Lal, Kerri G., Kim, Dohoon, Costanzo, Margaret C., Creegan, Matthew, Leeansyah, Edwin, Dias, Joana, Paquin-Proulx, Dominic, Eller, Leigh Anne, Schuetz, Alexandra, Phuang-ngern, Yuwadee, Krebs, Shelly J., Slike, Bonnie M., Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Kosgei, Josphat, Sacdalan, Carlo, Ananworanich, Jintanat, Bolton, Diane L., Michael, Nelson L., Shacklett, Barbara L., Robb, Merlin L., Eller, Michael A., Sandberg, Johan K.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959336/
https://ncbi.nlm.nih.gov/pubmed/31937782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13975-9
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