Treatment of human skeletal muscle cells with inhibitors of diacylglycerol acyltransferases 1 and 2 to explore isozyme-specific roles on lipid metabolism

Diacylglycerol acyltransferases (DGAT) 1 and 2 catalyse the final step in triacylglycerol (TAG) synthesis, the esterification of fatty acyl-CoA to diacylglycerol. Despite catalysing the same reaction and being present in the same cell types, they exhibit different functions on lipid metabolism in va...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Løvsletten, Nils G., Vu, Helene, Skagen, Christine, Lund, Jenny, Kase, Eili T., Thoresen, G. Hege, Zammit, Victor A., Rustan, Arild C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959318/
https://ncbi.nlm.nih.gov/pubmed/31937853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57157-5
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