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Unspecific DNA recombination in AdipoqCre-ER(T2) – mediated knockout approaches in transgenic mice is sex-, age- and genotype-dependent
Due to the epidemic rise of obesity prevalence, adipose tissue (AT) research is of major interest. Our aim was to study specificity of the most-common Cre/loxP approach for inducible gene manipulation of AT in mice (AdipoqCre-ER(T2)). We used mice with tamoxifen-sensitive Cre recombinase controlled...
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| 出版年: | Adipocyte |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959310/ https://ncbi.nlm.nih.gov/pubmed/31842670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623945.2019.1701394 |
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