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Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2α pathway

Iron is an essential element for all eukaryotic organisms because it participates as a redox active cofactor in a wide range of biological processes, including protein synthesis. Translation is probably the most energy consuming process in cells. Therefore, one of the initial responses of eukaryotic...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Romero, Antonia María, Ramos-Alonso, Lucía, Alepuz, Paula, Puig, Sergi, Martínez-Pastor, María Teresa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959253/
https://ncbi.nlm.nih.gov/pubmed/31937829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57132-0
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