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Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival

The thymus plays a significant role in establishing immunological self-tolerance. Previous studies have revealed that host immune reaction to allogeneic transplants could be regulated by thymus transplantation. However, physiological thymus involution hinders the clinical application of these insigh...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Otsuka, Ryo, Wada, Haruka, Tsuji, Hyuma, Sasaki, Airi, Murata, Tomoki, Itoh, Mizuho, Baghdadi, Muhammad, Seino, Ken-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959230/
https://ncbi.nlm.nih.gov/pubmed/31937817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57088-1
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