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Clonal hematopoiesis and risk of acute myeloid leukemia

Nearly all adults harbor acute myeloid leukemia (AML)-related clonal hematopoietic mutations at a variant allele fraction (VAF) of ≥0.0001, yet relatively few develop hematologic malignancies. We conducted a nested analysis in the Nurses’ Health Study and Health Professionals Follow-Up Study blood s...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Young, Andrew L., Tong, R. Spencer, Birmann, Brenda M., Druley, Todd E.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959179/
https://ncbi.nlm.nih.gov/pubmed/31004019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.215269
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