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Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus

The negative immune regulator Tollip inhibits the proinflammatory response to rhinovirus (RV) infection, a contributor to airway neutrophilic inflammation and asthma exacerbations, but the underlying molecular mechanisms are poorly understood. Tollip may inhibit IRAK1, a signaling molecule downstrea...

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Bibliografiske detaljer
Udgivet i:J Innate Immun
Main Authors: Dakhama, Azzeddine, Al Mubarak, Reem, Pavelka, Nicole, Voelker, Dennis, Seibold, Max, Ledford, Julie G., Kraft, Monica, Li, Liwu, Chu, Hong Wei
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959119/
https://ncbi.nlm.nih.gov/pubmed/30928973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000497072
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