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Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma

BACKGROUND: Chemo-resistance in hepatocellular carcinoma (HCC) is a major problem, and acquired drug resistance prevents cancer therapies from achieving complete responses. Molecular targeting therapy presents an opportunity to impede tumor through combination or sequential therapy, while the accura...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Liao, Xia, Song, Ge, Xu, Zihan, Bu, Yang, Chang, Fan, Jia, Fengan, Xiao, Xuelian, Ren, Xuejiao, Zhang, Mei, Jia, Qingan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958774/
https://ncbi.nlm.nih.gov/pubmed/31931755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6480-9
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