KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation

BACKGROUND: Histone lysine demethylase 4B (KDM4B) has been implicated in various pathological processes and human diseases. Glucose metabolism is the main pattern of energy supply in cells and its dysfunction is closely related to tumorigenesis. Recent study shows that KDM4B protects against obesity...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Li, Haijie, Lan, Jingqin, Wang, Guihua, Guo, Kaixuan, Han, Caishun, Li, Xiaolan, Hu, Junbo, Cao, Zhixin, Luo, Xuelai
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958723/
https://ncbi.nlm.nih.gov/pubmed/31931846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-1522-3
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