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Submicrometer Nanospray Emitters Provide New Insights into the Mechanism of Cation Adduction to Anionic Oligonucleotides
The electrospray-MS analysis of oligonucleotides is hampered by non-volatile metal cations, which may produce adducts responsible for signal suppression and loss of resolution. Alternative to replacing metal cations with MS-friendly ammonium, we explored the utilization of nanospray emitters with su...
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| Udgivet i: | Anal Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6958512/ https://ncbi.nlm.nih.gov/pubmed/30351906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b03632 |
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