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Role of the Metal Center in the Modulation of the Aggregation Process of Amyloid Model Systems by Square Planar Complexes Bearing 2-(2′-pyridyl)benzimidazole Ligands

The effect of analogue Pd(II)-, Pt(II)-, and Au(III) compounds featuring 2-(2′-pyridyl)benzimidazole on the aggregation propensity of amyloid-like peptides derived from Aβ and from the C-terminal domain of nucleophosmin 1 was investigated. Kinetic profiles of aggregation were evaluated using thiofla...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Florio, Daniele, Iacobucci, Ilaria, Ferraro, Giarita, Mansour, Ahmed M., Morelli, Giancarlo, Monti, Maria, Merlino, Antonello, Marasco, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958441/
https://ncbi.nlm.nih.gov/pubmed/31614832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12040154
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