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Involvement of spinal SIRT1 in development of chronic constriction injury induced neuropathic pain in rats

It is known that the epigenetic process of histone acetylation is involved in the neuropathic pain. The aim of this study was to determine whether sirtuin type 1 (SIRT1), an NAD(+) dependent deacetylase, affected allodynia and hyperalgesia in neuropathic pain. The neuropathic pain model was establis...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Luo, Feng-Qin, Ma, Qian, Zheng, Hui, Guo, Xiao-Wen, Zhang, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958300/
https://ncbi.nlm.nih.gov/pubmed/31938369
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