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Ouabain-induced apoptosis and inhibition of viability of tubulointerstitial cells by regulating NKA/pSrc/pERK/pAkt/pS6k/caspase 3 may contribute to lupus nephritis development

This study aimed to investigate the underlying molecular mechanism of ouabain-induced apoptosis and inhibited viability of tubulointerstitial cells in lupus nephritis (LN). Serum ouabain expression in 21 LN patients and 20 healthy controls (HCs) was detected by ELISA. Na-K-ATPase α1 (NKA) expression...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Liu, Changxuan, Lou, Meiyu, Ding, Yu, Wang, Yin, Huang, Yunfang, Shao, Danni, Chen, Wenli
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958254/
https://ncbi.nlm.nih.gov/pubmed/31938342
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