CD44(high)/ESA(low) squamous cell carcinoma cell-derived prostaglandin E(2) confers resistance to 5-fluorouracil-induced apoptosis in CD44(high)/ESA(high) cells

We previously found that CD44(high)/ESA(low) head and neck squamous cell carcinoma (HNSCC) cells harboring high dihydropyrimidine dehydrogenase (DPD) expression exhibited potent resistance to 5-fluorouracil (5-FU)-induced apoptosis. In addition, susceptibility of HNSCC cells to 5-FU was compromised...

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Detalles Bibliográficos
Publicado en:Int J Clin Exp Pathol
Main Authors: Shigeishi, Hideo, Hashikata, Miho, Yokoyama, Sho, Sakuma, Miyuki, Murozumi, Hiroshi, Kato, Hiroki, Rahman, Mohammad Zeshaan, Seino, Sayaka, Ishioka, Yasuki, Ohta, Kouji, Takechi, Masaaki, Sugiyama, Masaru
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2018
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958244/
https://ncbi.nlm.nih.gov/pubmed/31938347
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