LATS1 inhibits metastasis and epithelial-mesenchymal transition in head and neck squamous cell carcinoma

LATS1 is a serine/threonine kinase of the Hippo signaling pathway that phosphorylates and inactivates transcriptional co-activators YAP1 and WWTR1. To investigate roles of LATS1 expression in head and neck squamous cell carcinomas (HNSCCs), we transfected LATS1-expressing plasmid into B88 cells and...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Wu, Jicheng, Zhao, Zhijuan, Zhang, Huiling, Kong, Fanshuang, Jiang, Huamao, Huang, Keqiang, Zheng, Huachuan
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958224/
https://ncbi.nlm.nih.gov/pubmed/31938312
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