Intra-Articular Hyaluronic Acid and Chondroitin Sulfate: Pharmacokinetic Investigation in Osteoarthritic Rat Models

BACKGROUND: Viscosupplementation of synovial fluid with intra-articular (IA) injections of hyaluronic acid (HA) is widely used for symptomatic treatment of osteoarthritis (OA). Herein we present HCS, a new combination of chemicals, associating HA and chondroitin sulfate (CS), both members of the gly...

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Publicat a:Curr Ther Res Clin Exp
Autors principals: Fonsi, Massimiliano, El Amrani, Abdel-Ilah, Gervais, Frédéric, Vincent, Patrice
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957868/
https://ncbi.nlm.nih.gov/pubmed/31956378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2019.100573
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