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Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation

BACKGROUND & AIMS: Infections resulting from intestinal yeast and bacteria affect a large number of patients with deficits in absorptive or secretory epithelial transport mechanisms. The basolateral Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) has been implicated in intestinal epithelial fluid secret...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Koumangoye, Rainelli, Omer, Salma, Kabeer, Mustafa H., Delpire, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957845/
https://ncbi.nlm.nih.gov/pubmed/31655271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.10.006
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