The Hippo Kinase LATS2 Controls Helicobacter pylori-Induced Epithelial-Mesenchymal Transition and Intestinal Metaplasia in Gastric Mucosa

BACKGROUND & AIMS: Gastric carcinoma is related mostly to CagA+-Helicobacter pylori infection, which disrupts the gastric mucosa turnover and elicits an epithelial-mesenchymal transition (EMT) and preneoplastic transdifferentiation. The tumor suppressor Hippo pathway controls stem cell homeostas...

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Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Molina-Castro, Silvia Elena, Tiffon, Camille, Giraud, Julie, Boeuf, Hélène, Sifre, Elodie, Giese, Alban, Belleannée, Geneviève, Lehours, Philippe, Bessède, Emilie, Mégraud, Francis, Dubus, Pierre, Staedel, Cathy, Varon, Christine
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957828/
https://ncbi.nlm.nih.gov/pubmed/31669263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.10.007
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