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Improved Nucleic Acid Therapy with Advanced Nanoscale Biotechnology
Due to a series of systemic and intracellular obstacles in nucleic acid (NA) therapy, including fast degradation in blood, renal clearance, poor cellular uptake, and inefficient endosomal escape, NAs may need delivery methods to transport to the cell nucleus or cytosol to be effective. Advanced nano...
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| Publicado en: | Mol Ther Nucleic Acids |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957827/ https://ncbi.nlm.nih.gov/pubmed/31927331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.12.004 |
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